Description

Ethyl 3-(4-Fluorophenyl)-1-Methyl-1H-Pyrazole-5-Carboxylate is a high-purity fluorinated pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its precise molecular structure, which enables the development of novel active ingredients with targeted properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of new chemical entities and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorophenyl and pyrazole motifs contribute to biological activity and environmental stability.
• Material Science Research: Employed as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology & Probe Development: Serves as a scaffold for creating molecular probes and tool compounds used in biochemical assay development and target validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Ethyl 3-(4-Fluorophenyl)-1-Methyl-1H-Pyrazole-5-Carboxylate
CAS No.	943863-69-2
Molecular Formula	C13H13FN2O2
Molecular Weight	248.25 g/mol
Synonyms	Ethyl 1-methyl-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylate; 1-Methyl-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid ethyl ester; 5-Carbethoxy-1-methyl-3-(p-fluorophenyl)pyrazole; 3-(4-Fluorophenyl)-1-methyl-1H-pyrazole-5-carboxylic acid ethyl ester; 1H-Pyrazole-5-carboxylic acid, 3-(4-fluorophenyl)-1-methyl-, ethyl ester; Ethyl 3-(p-fluorophenyl)-1-methyl-1H-pyrazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Fluorophenyl)-1-Methyl-1H-Pyrazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.