Description

3-Hydroxypicolinoyl Chloride is a versatile and reactive chemical intermediate, primarily valued for its role as a key building block in the synthesis of complex organic molecules. Its functional groups make it a critical precursor for introducing the 3-hydroxypicolinoyl moiety into target compounds, enabling the development of advanced materials and active ingredients. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific heterocyclic structures.
• Ligand and Chelator Precursor: Serves as a starting material for creating specialized ligands used in catalysis, metal extraction, and diagnostic imaging agents.
• Material Science Research: Employed in the development of novel polymers, coatings, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Hydroxypicolinoyl Chloride
CAS No.	943777-92-2
Molecular Formula	C6H4ClNO2
Molecular Weight	157.55 g/mol
Synonyms	3-Hydroxypyridine-2-carbonyl chloride; 2-Pyridinecarbonyl chloride, 3-hydroxy-; 3-Hydroxy-2-pyridinecarbonyl chloride; 3-Hydroxypicolinic acid chloride; 3-Hydroxypicolinoyl chloride; 3-Hydroxy picolinoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxypicolinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.