Description

3-Ethynyl-Imidazo[1,2-A]Pyrazine is a high-purity, heterocyclic organic compound featuring a fused imidazopyrazine core with an ethynyl substituent. This unique structure makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Bioconjugation & Probe Development: The reactive ethynyl group enables its use in click chemistry for labeling biomolecules or creating diagnostic probes.
• Organic Electronic Materials: Potential building block for novel materials in organic light-emitting diodes (OLEDs) or semiconductors due to its conjugated system.
• Agrochemical Synthesis: Intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	3-Ethynyl-Imidazo[1,2-A]Pyrazine
CAS No.	943320-47-6
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	3-Ethynylimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 3-ethynyl-; 3-Ethynylimidazopyrazine; 3-Ethynyl-1H-imidazo[1,2-a]pyrazine; 3-Ethynyl-1H-imidazo[1,2-a]pyrazine (9CI); 943320-47-6; 3-Ethynylimidazo[1,2-a]pyrazine (major)
EINECS	Contact for details

Quality Control

Our 3-Ethynyl-Imidazo[1,2-A]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.