Description

4-Isoxazolecarboxylic Acid, 5-Cyclopropyl-3-Phenyl- is a high-value heterocyclic building block with a fused isoxazole and phenyl-cyclopropyl architecture. This compound matters as a critical synthetic intermediate for developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a core scaffold for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology & Proteomics: Employed as a versatile building block for creating chemical probes and tool compounds to study biological pathways.
• Academic & Contract Research: Essential for methodological development in organic synthesis and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Isoxazolecarboxylic Acid, 5-Cyclopropyl-3-Phenyl-
CAS No.	943130-42-5
Molecular Formula	C13H11NO3
Molecular Weight	229.23 g/mol
Synonyms	5-Cyclopropyl-3-phenylisoxazole-4-carboxylic acid; 3-Phenyl-5-cyclopropyl-4-isoxazolecarboxylic acid; 5-Cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid; 4-Carboxy-5-cyclopropyl-3-phenylisoxazole; 943130-42-5; AI3-52044; ZINC000103259509; SCHEMBL11827579; CTK8G7115
EINECS	Contact for details

Quality Control

Our 4-Isoxazolecarboxylic Acid, 5-Cyclopropyl-3-Phenyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.