Description

Ethyl 2-Methylene-5-Oxohexahydro-1H-Pyrrolizine-7A-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyrrolizine core structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of new drug candidates, particularly those targeting neurological and inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its complex heterocyclic structure for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, and fragrances requiring sophisticated molecular architectures.
• Academic & Contract Research: Essential for medicinal chemistry research, process chemistry optimization, and method development in laboratory settings.
• Bioconjugation & Probe Development: Its reactive methylene and ester groups make it suitable for creating chemical probes and bioconjugates for diagnostic applications.

Basic Information

Product Name	Ethyl 2-Methylene-5-Oxohexahydro-1H-Pyrrolizine-7A-Carboxylate
CAS No.	942603-91-0
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	Ethyl 2-methylenepyrrolizidine-7a-carboxylate; 7a-(Ethoxycarbonyl)-2-methylenepyrrolizidine-5-one; 2-Methylene-5-oxohexahydro-1H-pyrrolizine-7a-carboxylic Acid Ethyl Ester; 1H-Pyrrolizine-7a-carboxylic acid, 2,3,5,6,7,7a-hexahydro-2-methylene-5-oxo-, ethyl ester; Ethyl 2-methylene-5-oxo-1,2,3,5,6,7-hexahydro-7aH-pyrrolizine-7a-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Methylene-5-Oxohexahydro-1H-Pyrrolizine-7A-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.