Description

1H-Imidazole-5-Methanol, α-(1,1-Dimethylethyl)- is a specialized organic compound belonging to the imidazole class, characterized by its tert-butyl substituted methanol side chain. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis. It is primarily sought after by pharmaceutical and agrochemical research & development teams for the construction of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of new drug candidates, particularly those targeting enzymes and receptors where the imidazole moiety is critical for bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced fungicides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic frameworks, polymers, or ionic liquids with tailored properties.
• Chemical Biology Probes: Useful for modifying peptides or other biomolecules to study biological interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in bespoke, multi-step synthetic routes for clients.

Basic Information

Product Name	1H-Imidazole-5-Methanol, α-(1,1-Dimethylethyl)-
CAS No.	942495-07-0
Molecular Formula	C8H14N2O
Molecular Weight	154.21 g/mol
Synonyms	α-(tert-Butyl)-1H-imidazole-5-methanol; 2-(1,1-Dimethylethyl)-1H-imidazole-4-methanol; 4-(Hydroxymethyl)-2-tert-butylimidazole; 2-tert-Butyl-1H-imidazole-4-methanol; 2-tert-Butyl-4-(hydroxymethyl)imidazole; 4-(Hydroxymethyl)-2-(tert-butyl)-1H-imidazole; tert-Butylimidazolemethanol
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-5-Methanol, α-(1,1-Dimethylethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.