Description

1-(tert-Butoxycarbonyl)-3-Methoxy-3-Methylazetidine is a high-purity, protected azetidine building block of significant interest in advanced organic synthesis. This compound is valued for its role in constructing complex nitrogen-containing heterocycles, which are pivotal scaffolds in modern pharmaceutical discovery. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of azetidine-based drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides that incorporate the azetidine ring system.
• Medicinal Chemistry Research: Serves as a versatile building block for creating diverse chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetics Development: Employed in the synthesis of conformationally restricted peptide analogs to enhance metabolic stability and binding affinity.
• Ligand and Catalyst Preparation: Useful for preparing specialized nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-3-Methoxy-3-Methylazetidine
CAS No.	942307-80-4
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	1-Boc-3-Methoxy-3-Methylazetidine; 3-Methoxy-3-methylazetidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-methoxy-3-methylazetidine-1-carboxylate; 3-Methoxy-3-methyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester; Boc-3-Methoxy-3-Methylazetidine; 1-N-Boc-3-Methoxy-3-Methylazetidine; Azetidine, 3-methoxy-3-methyl-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-3-Methoxy-3-Methylazetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.