Description

(S)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its defined stereochemistry and functionalized pyrrolidine-phenoxy structure make it a valuable synthon for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate a specific enantiomer into their molecular designs.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold or ligand precursor for constructing complex molecules with high enantiomeric purity.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental profile.
• Chemical Biology & Proteomics: Employed as a molecular probe or a building block for activity-based protein profiling (ABPP) and other biochemical tools.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored optical or electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and chemical development projects requiring high-quality chiral intermediates.

Basic Information

Product Name	(S)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride
CAS No.	942194-84-5
Molecular Formula	C17H20ClNO
Molecular Weight	289.80 g/mol
Synonyms	(S)-3-(4-Benzylphenoxy)pyrrolidine HCl; (S)-3-(4-Benzylphenoxy)pyrrolidine hydrochloride; Pyrrolidine, 3-[(4-phenylmethyl)phenoxy]-, hydrochloride, (3S)-; (3S)-3-(4-Benzylphenoxy)pyrrolidine hydrochloride; (S)-3-(p-Benzylphenoxy)pyrrolidine hydrochloride; 942194-84-5; (S)-3-(4-Benzyl-phenoxy)-pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-3-(4-Benzylphenoxy)Pyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and mass spectrometry for structural confirmation, and stringent purity assays. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.