Description

Bucladesine (Calcium Salt) is a cell-permeable cyclic AMP (cAMP) analog that functions as a potent activator of protein kinase A (PKA). This compound is crucial for researchers investigating intracellular signaling pathways, particularly those related to cardiac function, neuronal activity, and cellular differentiation. It is primarily utilized in pharmaceutical R&D, biochemical research, and as a reference standard in analytical laboratories.

Application

• Pharmaceutical Research & Development: As a key intermediate or active pharmaceutical ingredient (API) in the development of cardioprotective and neuroprotective agents.
• Biochemical & Cell Biology Studies: Used as a research tool to study cAMP-mediated signal transduction, PKA activation, and related cellular processes in vitro.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in HPLC, LC-MS, and other chromatographic systems.
• Academic Research: Employed in university and institutional labs for fundamental research into heart disease, neuroscience, and cellular signaling mechanisms.

Basic Information

Product Name	Bucladesine (Calcium Salt)
CAS No.	938448-87-4
Molecular Formula	C18H23N5O8P·xCa
Molecular Weight	Contact for details
Synonyms	N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate calcium salt; Dibutyryl cAMP calcium salt; db-cAMP calcium salt; Bucladesine calcium; 2'-O-Dibutyryladenosine-3',5'-cyclic monophosphate calcium salt; N6,O2'-Dibutyryladenosine 3',5'-cyclic monophosphate calcium salt
EINECS	Contact for details

Quality Control

Our Bucladesine (Calcium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.