Description

Erlotinib is a potent and selective small-molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. This targeted therapeutic agent is critical for disrupting the signaling pathways that drive uncontrolled cell proliferation in certain cancers. It is primarily utilized in the pharmaceutical industry for the research, development, and production of oncology medications.

Application

• Active Pharmaceutical Ingredient (API): Primary use in the formulation of targeted cancer therapies.
• Oncology Research: A key reference standard and tool compound for studying EGFR signaling pathways and mechanisms of drug resistance.
• Pharmaceutical Development: Used in pre-clinical and clinical studies for new drug formulations and combination therapies.
• Bulk Drug Substance Manufacturing: Sourced by pharmaceutical companies for large-scale production of finished dosage forms.
• Biochemical Assays: Employed in high-throughput screening and enzymatic assays to evaluate EGFR inhibition.

Basic Information

Product Name	Erlotinib
CAS No.	938185-06-9
Molecular Formula	C22H23N3O4
Molecular Weight	393.44 g/mol
Synonyms	Erlotinib Hydrochloride; CP-358774; OSI-774; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; Tarceva (Brand Name); NSC 718781; EGFR Tyrosine Kinase Inhibitor
EINECS	Contact for details

Quality Control

Our Erlotinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.