Description

Ethanone,1-(2-Amino-4-Chloro-5-Fluorophenyl)- is a high-purity, halogenated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its precise molecular structure, featuring strategically placed amino, chloro, and fluoro substituents, makes it a critical building block for constructing complex pharmacologically active molecules. This compound is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

This versatile intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex halogenated scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro and fluoro groups enhance biological activity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for the development of specialized electron-transport or host materials in display and lighting technologies.
• Liquid Crystal & Dye Intermediate: Employed in the synthesis of advanced functional dyes and liquid crystal compounds for electronic displays.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Ethanone,1-(2-Amino-4-Chloro-5-Fluorophenyl)-
CAS No.	937816-87-0
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	1-(2-Amino-4-chloro-5-fluorophenyl)ethanone; 2-Acetylamino-4-chloro-5-fluorobenzene; 2'-Amino-4'-chloro-5'-fluoroacetophenone; 4-Chloro-5-fluoro-2-aminoacetophenone; 2-Amino-4-chloro-5-fluoroacetophenone; 1-(2-Amino-4-chloro-5-fluorophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our production of Ethanone,1-(2-Amino-4-Chloro-5-Fluorophenyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening sealed containers. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.