Description

2-Chloro-1,3-Bis(4-Fluorophenyl)Propane-1,3-Dione is a specialized fluorinated diketone derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and high-value building block for the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, where its unique halogenated and fluorinated structure enables precise modifications to enhance potency, selectivity, and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms can improve bioavailability and environmental persistence.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Advanced Material Precursor: Employed in the research and development of organic electronic materials and specialty polymers.
• Chemical Biology Probe Development: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-1,3-Bis(4-Fluorophenyl)Propane-1,3-Dione
CAS No.	937602-22-7
Molecular Formula	C15H9ClF2O2
Molecular Weight	294.68 g/mol
Synonyms	2-Chloro-1,3-bis(4-fluorophenyl)propane-1,3-dione; 1,3-Propanedione, 2-chloro-1,3-bis(4-fluorophenyl)-; 2-Chloro-1,3-di(4-fluorophenyl)-1,3-propanedione; 2-Chloro-1,3-bis(p-fluorophenyl)-1,3-propanedione; α-Chloro-4,4'-difluorodibenzoylmethane; 937602-22-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-Bis(4-Fluorophenyl)Propane-1,3-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.