Description

4,6-Quinazolinediamine, N6-(4,5-Dihydro-4,4-Dimethyl-2-Thiazolyl)-N4-[3-Methyl-4-([1,2,4]Triazolo[1,5-A]Pyridin-7-Yloxy)Phenyl]- is a high-purity, complex heterocyclic organic compound with the CAS number 937266-01-8. This advanced pharmaceutical intermediate is valued for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the research and development of targeted cancer therapies, leveraging its specific molecular structure.
• Kinase Inhibitor Development: Acts as a core scaffold or a functionalized component in the creation of novel kinase inhibitors.
• Chemical Biology & Proteomics: Employed in the design of chemical probes for studying disease pathways and protein functions.
• Preclinical & Clinical Trial Material: Supplied for the production of batches used in non-clinical studies and early-phase clinical trials.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Item	Details
Product Name	4,6-Quinazolinediamine, N6-(4,5-Dihydro-4,4-Dimethyl-2-Thiazolyl)-N4-[3-Methyl-4-([1,2,4]Triazolo[1,5-A]Pyridin-7-Yloxy)Phenyl]-
CAS No.	937266-01-8
Molecular Formula	C26H26N8OS
Molecular Weight	474.60 g/mol
Synonyms	N6-(4,5-Dihydro-4,4-dimethyl-2-thiazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine; 937266-01-8; 4,6-Quinazolinediamine derivative with thiazole and triazolopyridine; Advanced kinase inhibitor intermediate; [1,2,4]Triazolo[1,5-a]pyridine-7-ol quinazoline derivative
EINECS	Contact for details

Quality Control

Our 4,6-Quinazolinediamine derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.