Description

Glesatinib CAS NO 936694-12-1 is a potent and selective small molecule inhibitor targeting specific tyrosine kinases. This compound is of significant value in pharmaceutical research and development, particularly in the field of oncology. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in the discovery and development of novel cancer therapeutics.

Application

• Oncology Research: As a key active pharmaceutical ingredient (API) in preclinical and clinical studies for targeted cancer therapies.
• Biochemical Assay Development: Used as a reference standard or tool compound in high-throughput screening and mechanism-of-action studies.
• Pharmacology Studies: Employed in in vitro and in vivo models to investigate efficacy, pharmacokinetics, and pharmacodynamics.
• Drug Discovery Programs: Serves as a lead compound or intermediate in the synthesis of new chemical entities for therapeutic applications.
• Academic Research: Utilized in university and institutional labs for fundamental research on kinase signaling pathways.

Basic Information

Product Name	Glesatinib
CAS No.	936694-12-1
Molecular Formula	C₂₆H₂₈N₈O₂
Molecular Weight	484.55 g/mol
Synonyms	MGCD516; MGCD-516; 2-Pyrimidinamine, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinolinyl]oxy]phenyl]-4-(4-methyl-1-piperazinyl)-; UNII-2J4Q6QDK5K; Glesatinib (MGCD516); 2J4Q6QDK5K; N-[3-Fluoro-4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinolin-4-yl}oxy)phenyl]-4-(4-methylpiperazin-1-yl)pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our Glesatinib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure compliance with ICH guidelines for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator for long-term storage to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C limits
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.