Description

2-(2,4-Difluorophenoxy)-2-Methylpropanoyl Chloride is a specialized fluorinated acid chloride building block of significant importance in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-(2,4-difluorophenoxy)-2-methylpropanoyl moiety, a key structural motif in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, particularly in antifungal and antibacterial research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the difluorophenoxy group for enhanced biological activity.
• Peptide Mimetics & Prodrug Development: Serves as an acylating agent for creating amide bonds in complex peptide-like structures and prodrug formulations.
• Material Science Research: Employed in the synthesis of monomers or functional agents for specialty polymers with unique properties.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules in research applications due to its reactive acid chloride group.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom chemical synthesis services catering to diverse R&D needs.

Basic Information

Item	Details
Product Name	2-(2,4-Difluorophenoxy)-2-Methylpropanoyl Chloride
CAS No.	936327-47-8
Molecular Formula	C10H9ClF2O2
Molecular Weight	234.63 g/mol
Synonyms	2-Methyl-2-(2,4-difluorophenoxy)propanoyl chloride; α,α-Dimethyl-2,4-difluorophenoxyacetyl chloride; 2,4-Difluoro-α,α-dimethylphenoxyacetyl chloride; Propanoyl chloride, 2-(2,4-difluorophenoxy)-2-methyl-; 2-(2,4-Difluorophenoxy)isobutyryl chloride; (2,4-Difluorophenoxy)isobutyryl chloride; 2,4-DFPAC
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenoxy)-2-Methylpropanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.