Description

n-(tert-Butyl)-3-[[5-Methyl-2-[[4-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Benzenesulfonamide CAS NO 936091-15-5 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Research: Used as a reference standard or a tool compound in enzymatic assays and high-throughput screening (HTS) to study biological pathways.
• Medicinal Chemistry R&D: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the optimization of lead compounds for improved potency and selectivity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of active pharmaceutical ingredients (APIs) under stringent quality agreements.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	n-(tert-Butyl)-3-[[5-Methyl-2-[[4-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Benzenesulfonamide
CAS No.	936091-15-5
Molecular Formula	C26H34N6O3S
Molecular Weight	510.66 g/mol
Synonyms	N-(tert-Butyl)-3-((5-methyl-2-((4-(morpholinomethyl)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide; 936091-15-5; UNII-1Q0J8Q2Q6E; 1Q0J8Q2Q6E; Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-; N-(tert-butyl)-3-({5-methyl-2-[(4-{[4-(morpholin-4-yl)methyl]phenyl}amino)pyrimidin-4-yl]amino}benzene-1-sulfonamide; 3-[(2-{[4-(Morpholin-4-ylmethyl)phenyl]amino}-5-methylpyrimidin-4-yl)amino]-N-(tert-butyl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-3-[[5-Methyl-2-[[4-(4-Morpholinylmethyl)Phenyl]Amino]-4-Pyrimidinyl]Amino]Benzenesulfonamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.