Description

Cyclobutanol, 1-(2,6-Difluorophenyl)- is a high-value, fluorinated cyclobutanol derivative serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring a cyclobutanol ring substituted with a difluorophenyl group, makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Biology Probe: Utilized as a scaffold for creating molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	Cyclobutanol, 1-(2,6-Difluorophenyl)-
CAS No.	935287-84-6
Molecular Formula	C10H10F2O
Molecular Weight	184.18 g/mol
Synonyms	1-(2,6-Difluorophenyl)cyclobutanol; (2,6-Difluorophenyl)cyclobutanol; 1-(2,6-Difluorophenyl)cyclobutan-1-ol; α-(2,6-Difluorophenyl)cyclobutyl alcohol; Cyclobutan-1-ol, 1-(2,6-difluorophenyl)-; 935287-84-6
EINECS	Contact for details

Quality Control

Our Cyclobutanol, 1-(2,6-Difluorophenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.