Description

5-(Carboxyhydroxymethyl)Uridine is a modified nucleoside derivative, a key building block in advanced biochemical research and pharmaceutical development. This compound is valued for its role in synthesizing novel nucleotide analogs and exploring RNA structure-function relationships. It is essential for researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and diagnostic probe development.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a modified building block for studying RNA modification, structure, and enzymatic processing.
• Probe Development: Serves as a starting material for creating labeled nucleotides used in diagnostic assays and imaging.
• Enzymology Studies: Employed to investigate the substrate specificity and mechanism of nucleoside-metabolizing enzymes.
• Academic & Industrial R&D: Fundamental material for exploring new therapeutic modalities and bioconjugation techniques.

Basic Information

Product Name	5-(Carboxyhydroxymethyl)Uridine
CAS No.	934743-11-0
Molecular Formula	C11H14N2O9
Molecular Weight	318.24 g/mol
Synonyms	5-Carboxyhydroxymethyluridine; 5-(Hydroxymethylcarboxy)uridine; Uridine-5-carboxylic acid, hydroxymethyl-; 5-(1-Hydroxy-1-carboxymethyl)uridine; 5-(α-Hydroxy-α-carboxymethyl)uridine; 5-(HOOC-CH(OH)-)Uridine; 5-CHM-Uridine
EINECS	Contact for details

Quality Control

Our 5-(Carboxyhydroxymethyl)Uridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.