Description

Sulforhodamine 101 Acid Chloride is a highly reactive, functionalized derivative of the sulforhodamine 101 fluorophore, designed for covalent labeling applications. This compound is critical for researchers and manufacturers who require stable, site-specific fluorescent conjugation to biomolecules and materials. It is primarily utilized in the life sciences, diagnostics, and advanced materials sectors for creating high-performance fluorescent probes, sensors, and labels.

Application

• Bioconjugation and Probe Synthesis: Covalent labeling of proteins, antibodies, peptides, and oligonucleotides to create fluorescent conjugates for imaging and detection.
• Diagnostic Assay Development: Manufacturing fluorescent tags and detection reagents for ELISA, lateral flow assays, and other immunoassay platforms.
• Bioimaging and Cell Biology: Preparation of cell-permeable or targeted fluorescent dyes for live-cell imaging, super-resolution microscopy, and flow cytometry.
• Polymer and Material Science: Functionalization of nanoparticles, polymers, and surfaces to impart fluorescence for tracking, sensing, or security applications.
• Chemical Biology Research: A key building block for developing activity-based probes (ABPs) and other tools to study enzyme activity and biomolecular interactions.

Basic Information

Product Name	Sulforhodamine 101 Acid Chloride
CAS No.	934482-80-1
Molecular Formula	C₃₁H₂₉ClN₂O₆S₂
Molecular Weight	625.15 g/mol
Synonyms	Sulforhodamine 101 sulfonyl chloride; Texas Red-X sulfonyl chloride; Texas Red sulfonyl chloride; Texas Red-X, SE; Sulforhodamine 101 sulfonic acid chloride; 5-(and-6)-Sulforhodamine 101 acid chloride; Texas Red dye acid chloride; 2-[6-(Diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl]-5-sulfobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our Sulforhodamine 101 Acid Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional testing for labeling efficiency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain reactivity and stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Dark red to purple solid or powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Anhydrous basis)
Water Content (KF)	≤ 1.0%
Functional Activity (Labeling)	Conforms to reference standard
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.