Description

3'-β-C-Methyl-5-Methyluridine is a chemically modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of nucleoside-based drugs, particularly for targeting RNA viruses. The compound is supplied with a guaranteed CAS No. 934002-35-4 for precise identification and traceability.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of modified nucleoside analogs with antiviral and anticancer activities.
• Antiviral Drug Research: Used in the R&D of therapeutics targeting RNA viruses, such as Hepatitis C Virus (HCV), by acting as a chain terminator or inhibitor of viral polymerase.
• Biochemical Research: Employed in studies investigating RNA metabolism, nucleotide transport, and the mechanisms of nucleoside-based therapeutics.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and metabolic stability.
• Pro-drug Synthesis: Utilized in the design and synthesis of pro-drug forms to enhance the bioavailability and pharmacokinetic profile of active nucleoside drugs.

Basic Information

Product Name	3'-β-C-Methyl-5-Methyluridine
CAS No.	934002-35-4
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	3'-C-Methyl-5-methyluridine; 5-Methyl-3'-C-methyluridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl)-5-methylpyrimidine-2,4-dione; 3'-Deoxy-3'-C-methyl-5-methyluridine; β-C-Methyl-5-methyluridine; 3'-C-Me-5-Me-uridine; 3'-β-C-Methyl-5-methyluridine
EINECS	Contact for details

Quality Control

Our 3'-β-C-Methyl-5-Methyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.