Description

4-Bromo-2-Trifluoromethylbenzyl Alcohol is a versatile and high-value fluorinated aromatic building block. This compound is essential for introducing both bromine and trifluoromethyl functional groups into complex molecular architectures, enabling precise tuning of physical and chemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Organic Synthesis & Research: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating novel chemical entities.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to develop specialty polymers with unique solubility, thermal, and surface properties.

Basic Information

Product Name	4-Bromo-2-Trifluoromethylbenzyl Alcohol
CAS No.	932390-36-8
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	(4-Bromo-2-(trifluoromethyl)phenyl)methanol; 2-Trifluoromethyl-4-bromobenzyl Alcohol; 1-Bromo-4-(hydroxymethyl)-3-(trifluoromethyl)benzene; α-Hydroxy-4-bromo-α,α,α-trifluoro-o-xylene; 4-Bromo-α,α,α-trifluoro-o-toluyl Alcohol; 4-Bromo-2-trifluoromethylbenzenemethanol
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Trifluoromethylbenzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.