Description

n-[2-(Bromomethyl)-5-Fluorophenyl]-2,2,2-Trifluoroacetimidoyl Chloride CAS NO 930778-46-4 is a high-value, multi-functional halogenated aromatic building block designed for advanced synthetic chemistry. This compound is critical for introducing both bromomethyl and trifluoroacetimidoyl chloride functional groups in a single, controlled reaction step, enabling efficient construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct novel herbicides and pesticides where the fluorine and bromine atoms contribute to bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating activity-based probes and other tools for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and small-scale GMP batches.

Basic Information

Product Name	n-[2-(Bromomethyl)-5-Fluorophenyl]-2,2,2-Trifluoroacetimidoyl Chloride
CAS No.	930778-46-4
Molecular Formula	C10H7BrClF4NO
Molecular Weight	332.52 g/mol
Synonyms	2-(Bromomethyl)-5-fluoro-N-(trichloroacetyl)aniline; 1-[2-(Bromomethyl)-5-fluorophenyl]-2,2,2-trifluoroethanimidoyl chloride; 5-Fluoro-2-(bromomethyl)phenyl(trifluoroacetyl)imino chloride; 2-Bromomethyl-5-fluorophenyl trifluoroacetimidoyl chloride; N-(2-Bromomethyl-5-fluorophenyl)-2,2,2-trifluoroacetimidoyl chloride; Trifluoroacetimidoyl chloride derivative of 2-bromomethyl-5-fluoroaniline
EINECS	Contact for details

Quality Control

Every batch of n-[2-(Bromomethyl)-5-Fluorophenyl]-2,2,2-Trifluoroacetimidoyl Chloride is manufactured and tested under a strict quality management system. We ensure high purity and lot-to-lot consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.