Description

(4-(Chloromethyl)Phenyl)(Pyrrolidin-1-Yl)Methanone is a high-value organic building block featuring a chloromethyl group and a pyrrolidine amide moiety, making it a versatile intermediate for advanced synthesis. This compound is critical for pharmaceutical research and development, enabling the construction of complex molecules with potential biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the chloromethyl group allows for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Polymer Modification: The reactive chloromethyl group enables its use as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Academic & Contract Research: Essential reagent in university laboratories and CROs (Contract Research Organizations) for exploratory organic synthesis and method development.

Basic Information

Product Name	(4-(Chloromethyl)Phenyl)(Pyrrolidin-1-Yl)Methanone
CAS No.	929972-98-5
Molecular Formula	C12H14ClNO
Molecular Weight	223.70 g/mol
Synonyms	1-(4-(Chloromethyl)benzoyl)pyrrolidine; 4-(Chloromethyl)-N-pyrrolidinylbenzamide; 4-(Chloromethyl)benzoic acid pyrrolidide; 4-(Chloromethyl)benzoyl pyrrolidine; Pyrrolidin-1-yl[4-(chloromethyl)phenyl]methanone; 929972-98-5; 4-Chloromethylphenyl pyrrolidin-1-yl ketone
EINECS	Contact for details

Quality Control

Our (4-(Chloromethyl)Phenyl)(Pyrrolidin-1-Yl)Methanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced intermediates used in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.