Description

(3-Bromo-4-Fluorophenyl)(Cyclopropyl)Methanol is a high-value, multi-functional chiral building block and intermediate in advanced organic synthesis. Its structure, featuring a bromo-fluoro aromatic system and a chiral alcohol moiety, makes it a critical precursor for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated aromatic system.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the synthesis of specialty polymers and liquid crystals, where the cyclopropyl and fluorinated groups impart unique physical properties.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects requiring specific bromo-fluoro substitution patterns.

Basic Information

Product Name	(3-Bromo-4-Fluorophenyl)(Cyclopropyl)Methanol
CAS No.	929884-48-0
Molecular Formula	C10H10BrFO
Molecular Weight	245.09 g/mol
Synonyms	Cyclopropyl(3-bromo-4-fluorophenyl)methanol; (3-Bromo-4-fluorophenyl)(cyclopropyl)carbinol; 1-(3-Bromo-4-fluorophenyl)-1-cyclopropylmethanol; α-Cyclopropyl-3-bromo-4-fluorobenzyl alcohol; (3-Br-4-F-C6H3)(c-C3H5)CHOH
EINECS	Contact for details

Quality Control

Our (3-Bromo-4-Fluorophenyl)(Cyclopropyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.