Description

(1S)-1-(3-Bromo-4-Fluorophenyl)Ethan-1-Ol CAS NO 929884-46-8 is a high-purity chiral intermediate characterized by its bromo- and fluoro-substituted aromatic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine and bromine substituents for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty monomers for advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	(1S)-1-(3-Bromo-4-Fluorophenyl)Ethan-1-Ol
CAS No.	929884-46-8
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	(S)-1-(3-Bromo-4-fluorophenyl)ethanol; (1S)-1-(3-Bromo-4-fluorophenyl)ethanol; (-)-1-(3-Bromo-4-fluorophenyl)ethanol; (S)-(-)-1-(3-Bromo-4-fluorophenyl)ethanol; 3-Bromo-4-fluoro-α-methylbenzyl alcohol (S)-form; 929884-46-8; (S)-3-Bromo-4-fluoro-α-methylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our (1S)-1-(3-Bromo-4-Fluorophenyl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.