Description

1-[2-(Difluoromethoxy)Phenyl]Propan-1-One is a specialized organic building block featuring a difluoromethoxy-substituted aromatic ketone structure. This compound is valued for its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought by research and development chemists and process engineers in the fine chemical and life science industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and ligands for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-[2-(Difluoromethoxy)Phenyl]Propan-1-One
CAS No.	929341-33-3
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	1-[2-(Difluoromethoxy)phenyl]-1-propanone; 2-(Difluoromethoxy)propiophenone; Propiophenone, 2'-(difluoromethoxy)-; 1-Propanone, 1-[2-(difluoromethoxy)phenyl]-; α,α-Difluoro-2-methoxypropiophenone; DFMPP (abbreviation); 929341-33-3; 1-(2-(Difluoromethoxy)phenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our 1-[2-(Difluoromethoxy)Phenyl]Propan-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.