Description

1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethanone is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. Its value lies in its unique structure, which incorporates both electron-donating methoxy groups and the highly electron-withdrawing trifluoroacetyl moiety, making it an essential intermediate for constructing complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a key precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands and catalysts for asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where the trifluoromethyl group imparts desirable thermal and electronic properties.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on understanding and exploiting fluorine atom interactions in molecular design.
• Custom Synthesis and Contract Manufacturing: A requested starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethanone
CAS No.	929099-06-9
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	3',5'-Dimethoxy-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3,5-dimethoxyphenyl)ethanone; 1-(3,5-Dimethoxyphenyl)-2,2,2-trifluoroethan-1-one; 3,5-Dimethoxyphenyl trifluoromethyl ketone; Trifluoro(3,5-dimethoxyphenyl)methanone; (3,5-Dimethoxyphenyl)(trifluoromethyl)methanone; TFAP-DM
EINECS	Contact for details

Quality Control

Our 1-(3,5-Dimethoxyphenyl)-2,2,2-Trifluoroethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.