Description

1-(2-Bromo-6-Fluorophenyl)Ethanone is a high-purity fluorinated and brominated aromatic ketone building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The ketone group allows for further derivatization to alcohols, alkenes, and other functional groups, expanding its utility in multi-step syntheses.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical and chemical analysis.

Basic Information

Product Name	1-(2-Bromo-6-Fluorophenyl)Ethanone
CAS No.	928715-37-1
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2'-Bromo-6'-fluoroacetophenone; 2-Bromo-6-fluoroacetophenone; 1-Acetyl-2-bromo-6-fluorobenzene; Ethanone, 1-(2-bromo-6-fluorophenyl)-; 2-Bromo-6-fluorophenyl methyl ketone; α-Bromo-α'-fluoroacetophenone (isomer specific); (2-Bromo-6-fluorophenyl)(oxo)methane
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-6-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using inert atmosphere packaging to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.