Description

7-(2-Azido-1-Hydroxyethyl)-4-(Benzyloxy)Benzo[D]Thiazol-2(3H)-One is a specialized organic compound featuring a benzothiazolone core functionalized with azido and benzyloxy groups. This unique structure makes it a valuable pharmaceutical intermediate and click chemistry building block, enabling the synthesis of complex molecules for drug discovery and materials science. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Click Chemistry Reagent: The azido group enables efficient, modular conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer chemistry.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a versatile linker component in the design of bifunctional molecules for targeted protein degradation.
• Fluorescent Probe Synthesis: Used to construct advanced molecular probes for bioimaging and diagnostic applications.
• Agrochemical Research: Intermediate in the development of new active ingredients with enhanced efficacy.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry programs and novel material development in research laboratories.

Basic Information

Product Name	7-(2-Azido-1-Hydroxyethyl)-4-(Benzyloxy)Benzo[D]Thiazol-2(3H)-One
CAS No.	928663-80-3
Molecular Formula	C₁₆H₁₄N₄O₃S
Molecular Weight	342.37 g/mol
Synonyms	4-(Benzyloxy)-7-(2-azido-1-hydroxyethyl)-2,3-dihydro-1,3-benzothiazol-2-one; 7-(2-Azido-1-hydroxyethyl)-4-(benzyloxy)-2,3-dihydro-1,3-benzothiazol-2-one; 4-Benzyloxy-7-(2-azido-1-hydroxyethyl)benzothiazol-2(3H)-one; 928663-80-3; Benzothiazolone azide derivative; Azido-functionalized benzothiazolone; BnO-BTAz-OH
EINECS	Contact for details

Quality Control

Our production of 7-(2-Azido-1-Hydroxyethyl)-4-(Benzyloxy)Benzo[D]Thiazol-2(3H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural integrity. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting GMP-grade applications where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.