Description

[3-(Difluoromethoxy)-4-Methoxyphenyl]Methanol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique difluoromethoxy and methoxy substituents, which are critical for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Intermediate: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and environmental stability.
• Liquid Crystal Material Precursor: Serves as a starting material for the synthesis of fluorinated aromatic cores used in high-performance liquid crystal displays (LCDs).
• Organic Electronic Material Synthesis: Employed in the development of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns requiring specialized fluorinated aromatics.
• Chemical Research & Development: Utilized in academic and industrial labs to explore new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	[3-(Difluoromethoxy)-4-Methoxyphenyl]Methanol
CAS No.	926189-53-9
Molecular Formula	C9H10F2O3
Molecular Weight	204.17 g/mol
Synonyms	(3-(Difluoromethoxy)-4-methoxyphenyl)methanol; 4-Methoxy-3-(difluoromethoxy)benzyl alcohol; 3-(Difluoromethoxy)-4-methoxybenzenemethanol; α,α-Difluoro-4-methoxy-m-anisyl alcohol; Benzenemethanol, 3-(difluoromethoxy)-4-methoxy-; DFMMBA (abbreviation); Fluorinated Benzyl Alcohol Derivative
EINECS	Contact for details

Quality Control

Our [3-(Difluoromethoxy)-4-Methoxyphenyl]Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.