Description

Radotinib is a potent and selective small-molecule tyrosine kinase inhibitor. This compound is of significant interest in pharmaceutical research and development, particularly in the field of oncology. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of novel therapeutic agents and advanced intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of targeted cancer therapies.
• Oncology Research: Used as a reference standard or active ingredient in preclinical studies targeting specific kinase pathways.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) to identify and characterize kinase inhibitors.
• Mechanism of Action Studies: A critical tool for investigating cellular signaling pathways and drug resistance mechanisms.
• Process Chemistry & Scale-Up: Utilized in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Formulation Development: Investigated in the creation of dosage forms for clinical trial materials.

Basic Information

Item	Detail
Product Name	Radotinib
CAS No.	926037-48-1
Molecular Formula	C₂₉H₃₁N₇O
Molecular Weight	493.60 g/mol
Synonyms	Radotinib; IY-5511; Supect; 2-{4-[4-(4-Methylpiperazin-1-yl)phenylamino]pyrimidin-2-ylamino}-5-(4-methylphenyl)thiazole-4-carboxamide; 2-({4-[4-(4-Methyl-1-piperazinyl)phenyl]amino}-2-pyrimidinyl)amino)-5-(4-methylphenyl)-4-thiazolecarboxamide
EINECS	Contact for details

Quality Control

Our Radotinib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and MS, to ensure it meets high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.