Description

4-[(2-Fluorobenzyl)Oxy]-3-Methoxybenzoyl Chloride is a high-purity, reactive benzoyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile acylating agent, enabling the efficient introduction of a specific substituted benzoyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific fluorinated aromatic structures.
• Peptide Coupling Reagent: Acts as an acyl chloride activator in peptide synthesis and other amide bond formation reactions.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays.
• Polymer Modification: Employed to introduce functional groups onto polymer backbones to alter material properties.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	4-[(2-Fluorobenzyl)Oxy]-3-Methoxybenzoyl Chloride
CAS No.	926028-23-1
Molecular Formula	C16H14ClFO3
Molecular Weight	308.73 g/mol
Synonyms	3-Methoxy-4-[(2-fluorobenzyl)oxy]benzoyl chloride; 4-(2-Fluorobenzyloxy)-3-methoxybenzoyl chloride; 2-Fluoro-α-[(4-(chlorocarbonyl)-2-methoxyphenoxy]methyl]benzene; Benzoyl chloride, 4-[(2-fluorobenzyl)oxy]-3-methoxy-; 926028-23-1
EINECS	Contact for details

Quality Control

Every batch of 4-[(2-Fluorobenzyl)Oxy]-3-Methoxybenzoyl Chloride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) including purity (HPLC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.