Description

Methyl Chloroformate is a versatile and highly reactive organic reagent, primarily used as a key methylating and carbonylating agent in chemical synthesis. Its value lies in its ability to efficiently introduce the methoxycarbonyl group, making it indispensable for constructing complex molecular frameworks. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediates: A crucial reagent in the synthesis of various active pharmaceutical ingredients (APIs), including carbamate prodrugs and protecting groups for amines.
• Agrochemical Synthesis: Used in the production of herbicides, insecticides, and fungicides, where it acts as a methoxycarbonylation agent.
• Polymer Chemistry: Employed as a monomer or modifying agent in the production of specialty polymers, polycarbonates, and polyurethanes.
• Fine Chemical Manufacturing: Serves as a fundamental building block for dyes, pigments, and other high-value specialty chemicals.
• Organic Synthesis: Widely used in laboratories for esterification reactions and the preparation of carboxylic acid derivatives under mild conditions.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process development for novel compound libraries.

Basic Information

Product Name	Methyl Chloroformate
CAS No.	79-22-1
Molecular Formula	C2H3ClO2
Molecular Weight	94.50 g/mol
Synonyms	Methyl chlorocarbonate; Chloroformic acid methyl ester; Methoxycarbonyl chloride; Methyl carbonochloridate; Carbonochloridic acid, methyl ester; MCF; Methyl ester of chloroformic acid
EINECS	201-187-3

Quality Control

Our Methyl Chloroformate is manufactured under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including gas chromatography (GC), to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your need for reliable and reproducible results in critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to maintain product integrity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.1%
Density (at 20°C)	1.21 - 1.23 g/mL
Refractive Index (n20D)	1.386 - 1.388

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.