Description

Bromoacetyl Chloride is a highly reactive bifunctional reagent, serving as a crucial building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce both bromo and acyl chloride functionalities, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), herbicides, and polymer precursors.

Application

• Pharmaceutical Intermediates: Key starting material for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, pesticides, and plant growth regulators by acting as an acylating and alkylating agent.
• Peptide Modification & Bioconjugation: Employed to introduce reactive handles onto peptides, proteins, and other biomolecules for labeling, cross-linking, or affinity purification.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and functional materials.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation, nucleophilic substitution reactions, and the preparation of heterocyclic compounds.
• Chemical Research & Development: Fundamental tool in medicinal chemistry and process development for creating novel chemical entities and optimizing synthetic routes.

Basic Information

Product Name	Bromoacetyl Chloride
CAS No.	22118-09-8
Molecular Formula	C2H2BrClO
Molecular Weight	157.39 g/mol
Synonyms	Bromoacetyl chloride; Bromoacetic acid chloride; 2-Bromoacetyl chloride; α-Bromoacetyl chloride; Bromoacetic chloride; Monobromoacetyl chloride; Acetyl chloride, bromo-; Bromoethanoyl chloride
EINECS	244-788-8

Quality Control

Our Bromoacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including assay (by titration or GC), identity confirmation (IR), and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified. This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/Titration)	≥ 98.0%
Color (APHA)	≤ 50
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.