Description

Acitretin (Sodium) is the sodium salt form of acitretin, a second-generation retinoid. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on dermatology and oncology. The product is supplied to the global market with a focus on high purity and reliable supply chain integrity.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for severe dermatological conditions.
• Dermatological Research: Key compound in R&D for novel treatments targeting psoriasis, keratinization disorders, and other skin diseases.
• Oncological Research: Investigated for its potential effects on cell differentiation and proliferation in cancer studies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.
• Intermediate Synthesis: Used in the synthesis of more complex retinoid derivatives and prodrug formulations.
• Preclinical & Clinical Studies: Essential material for pharmacokinetic, pharmacodynamic, and toxicological evaluations.

Basic Information

Product Name	Acitretin (Sodium)
CAS No.	925701-88-8
Molecular Formula	C21H25NaO3
Molecular Weight	348.41 g/mol
Synonyms	Acitretin Sodium Salt; Sodium Acitretin; (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate Sodium Salt; Neotigason Sodium; Soriatane Sodium; Ro 10-1670 Sodium Salt; Etretin Sodium; All-trans-acitretin Sodium
EINECS	Contact for details

Quality Control

Our Acitretin (Sodium) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR), to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) are provided with every shipment, detailing full compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen) in the original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.