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Anthralin CAS NO 1143-38-0


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CAS No.:1143-38-0

Grade:Pharmacy Grade

Content:99.0%

Brand:Customizable

Packaging:Customizable

Description

Anthralin is a synthetic hydroxyanthrone derivative with significant biological activity, primarily recognized for its therapeutic effects on hyperproliferative skin conditions. Its value lies in its potent ability to normalize keratinocyte differentiation and modulate immune responses, making it a key active pharmaceutical ingredient (API) for targeted dermatological treatments. This compound is essential for manufacturers in the pharmaceutical industry developing topical formulations for psoriasis and other dermatoses, as well as for research institutions studying cell proliferation mechanisms.

Application

  • Topical Pharmaceutical Formulations: Primary use as the active ingredient in creams, ointments, and pastes for the treatment of plaque psoriasis.
  • Dermatological Research: A critical tool in biochemical and pharmacological studies investigating anti-proliferative and anti-inflammatory pathways in skin cells.
  • API Synthesis: Serves as a key intermediate or final active pharmaceutical ingredient (API) in the production of specialty dermatological drugs.
  • Veterinary Medicine: Used in topical preparations for managing similar hyperproliferative skin disorders in animals.
  • Cosmeceutical Development: Investigated for potential use in products aimed at managing scalp conditions and other mild skin irregularities.

Basic Information

Product Name Anthralin
CAS No. 1143-38-0
Molecular Formula C14H10O3
Molecular Weight 226.23 g/mol
Synonyms Dithranol; 1,8,9-Anthracenetriol; 1,8-Dihydroxy-9-anthrone; Cignolin; Anthra-Derm; Drithocreme; Psoriacide; 1,8,9-Trihydroxyanthracene
EINECS 214-528-0

Quality Control

Our Anthralin is manufactured under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with various pharmacopeial monographs, and customized specifications are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened.

Specification

Item Specification
Appearance Yellow to brownish-yellow crystalline powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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