Description

Retinoic Acid is a potent and biologically active metabolite of Vitamin A, essential for cellular growth, differentiation, and immune function. This high-purity compound is critical for research and development in life sciences and for the formulation of advanced pharmaceutical and cosmetic products. It serves as a key ingredient for pharmaceutical manufacturers, R&D laboratories, and specialty chemical producers focused on dermatology, oncology, and cell biology applications.

Application

• Pharmaceutical Active Ingredient (API): Core component in topical and systemic formulations for treating acne, psoriasis, and photoaged skin.
• Cell Culture & Differentiation Research: Essential reagent in stem cell research and studies of cellular differentiation and proliferation.
• Dermatological & Cosmetic Formulations: Used in anti-aging serums, creams, and treatments for its ability to promote collagen production and skin renewal.
• Biochemical Research: Ligand for nuclear retinoic acid receptors (RARs/RXRs) in studies of gene expression and signaling pathways.
• Oncology Research: Investigated for its role in cancer cell differentiation and as a potential therapeutic agent in certain leukemias.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing.

Basic Information

Product Name	Retinoic Acid
CAS No.	302-79-4
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	all-trans-Retinoic Acid; Tretinoin; Vitamin A Acid; Retin-A; Aberela; Airol; ATRA; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
EINECS	206-129-0

Quality Control

Our Retinoic Acid is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Allow the container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (all-trans isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
13-cis-Retinoic Acid	≤1.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.