Description

4-Isopropylthiazole-2-Carbonyl Chloride is a highly reactive and versatile acid chloride derivative used as a key synthetic intermediate. Its value lies in enabling the efficient construction of complex amide and ester bonds, particularly in the synthesis of novel heterocyclic compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those containing thiazole and amide pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the isopropylthiazole moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials requiring specific heterocyclic units.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.
• Academic and R&D Laboratories: Used in medicinal chemistry and organic synthesis research to explore new chemical entities and reaction pathways.

Basic Information

Product Name	4-Isopropylthiazole-2-Carbonyl Chloride
CAS No.	923289-59-2
Molecular Formula	C7H8ClNOS
Molecular Weight	189.66 g/mol
Synonyms	2-Isopropyl-1,3-thiazole-4-carbonyl chloride; 4-(1-Methylethyl)-2-thiazolecarbonyl chloride; 2-Isopropylthiazole-4-carboxylic acid chloride; 4-Isopropyl-2-thiazolecarbonyl chloride; 4-Isopropylthiazole-2-carboxylic acid chloride; 2-Thiazolecarbonyl chloride, 4-(1-methylethyl)-; 923289-59-2
EINECS	Contact for details

Quality Control

Our 4-Isopropylthiazole-2-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.