Description

1-Methyl-5-Phenoxy-3-(Trifluoromethyl)-1H-Pyrazole-4-Carbonyl Chloride is a high-value, reactive chemical intermediate characterized by its pyrazole core and acid chloride functionality. This compound matters for its role as a critical building block in the synthesis of advanced, high-performance molecules, particularly in the agrochemical and pharmaceutical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, including pesticides, herbicides, and specialized pharmaceutical candidates. The compound's structure offers a versatile handle for further derivatization, enabling the creation of complex target molecules with specific biological activities.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel pyrazole-based insecticides, herbicides, and fungicides, leveraging the trifluoromethyl group for enhanced bioactivity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry research for constructing active pharmaceutical ingredients (APIs) targeting various disease pathways, where the phenoxy and pyrazole motifs are pharmacologically relevant.
• Specialty Chemical Synthesis: Serves as a versatile reagent for introducing the 1-methyl-5-phenoxy-3-(trifluoromethyl)pyrazole moiety into dyes, pigments, or functional materials.
• Research & Development: Employed in academic and industrial R&D laboratories for method development and exploring new chemical entities in life sciences.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules at various scales.

Basic Information

Product Name	1-Methyl-5-Phenoxy-3-(Trifluoromethyl)-1H-Pyrazole-4-Carbonyl Chloride
CAS No.	921939-09-5
Molecular Formula	C12H8ClF3N2O2
Molecular Weight	304.65 g/mol
Synonyms	1-Methyl-5-phenoxy-3-(trifluoromethyl)-1H-pyrazole-4-carbonyl chloride; 1-Methyl-5-phenoxy-3-trifluoromethyl-1H-pyrazole-4-carbonyl chloride; 4-Carbonyl chloride-1-methyl-5-phenoxy-3-trifluoromethylpyrazole; 1H-Pyrazole-4-carbonyl chloride, 1-methyl-5-phenoxy-3-(trifluoromethyl)-; Pyrazole-4-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Phenoxy-3-(Trifluoromethyl)-1H-Pyrazole-4-Carbonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets precise customer specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to supply chain integrity and batch-to-batch consistency supports your development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.