Description

3-(2-Bromophenyl)Cyclobutan-1-One is a high-purity, synthetically valuable brominated cyclobutanone derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications requiring precise structural control.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers with tailored properties.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including ring-expansion and cross-coupling reactions.

Basic Information

Product Name	3-(2-Bromophenyl)Cyclobutan-1-One
CAS No.	918299-24-8
Molecular Formula	C10H9BrO
Molecular Weight	225.08 g/mol
Synonyms	2-Bromophenyl Cyclobutanone; 1-(2-Bromophenyl)cyclobutan-1-one; 3-(2-Bromophenyl)cyclobutanone; Cyclobutanone, 3-(2-bromophenyl)-; 2-Bromo-alpha,α-dimethylbenzenemethanol (related); 2-Bromobenzoylcyclopropane (precursor); (2-Bromophenyl)(cyclobutyl)methanone; 918299-24-8
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Bromophenyl)Cyclobutan-1-One is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.