Description

2-Methyl-1,3-thiazole-4-carbonyl chloride hydrochloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its primary value lies in its role as a key acylating agent for introducing the 2-methylthiazole-4-carbonyl moiety, a structural motif of significant interest in medicinal chemistry. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals. We supply this material with a focus on consistent quality and reliable availability to support your complex synthesis projects.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the bioactive thiazole core.
• Fine Chemical Production: Serves as a specialized acylating agent in the manufacture of complex, high-value organic compounds.
• Research & Development: Employed in academic and industrial R&D labs for constructing heterocyclic compounds and exploring structure-activity relationships.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands or catalyst precursors containing the thiazole functionality.

Basic Information

Item	Details
Product Name	2-Methyl-1,3-thiazole-4-carbonyl chloride hydrochloride
CAS No.	917483-72-8
Molecular Formula	C6H5Cl2NOS
Molecular Weight	210.08 g/mol
Synonyms	2-Methyl-4-thiazolecarbonyl chloride hydrochloride; 2-Methylthiazole-4-carbonyl chloride hydrochloride; 4-Thiazolecarbonyl chloride, 2-methyl-, hydrochloride; 2-Methyl-1,3-thiazole-4-carboxylic acid chloride hydrochloride; 2-Methyl-4-carboxythiazole chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,3-thiazole-4-carbonyl chloride hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.