Description

Bicyclo[2.2.1]Heptane-2-Acetyl Fluoride is a specialized fluorinated organic building block derived from the norbornane (bicyclo[2.2.1]heptane) scaffold. This compound is valued for its unique structural rigidity and the reactivity of its acetyl fluoride functional group, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with defined three-dimensional architecture.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with complex, strained ring systems, particularly in neurology and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the norbornane core contributes to biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers with high thermal stability and specific optical properties.
• Fluorination Chemistry: The acetyl fluoride moiety acts as an efficient acylating agent or a handle for further fluorination reactions in fine chemical synthesis.
• Catalyst & Ligand Development: Utilized as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: Essential for methodological studies and exploring new reaction pathways in organic and medicinal chemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Acetyl Fluoride
CAS No.	917373-36-5
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	2-Acetylfluoronorbornane; 2-(Fluoroacetyl)bicyclo[2.2.1]heptane; Norbornane-2-acetyl fluoride; Bicyclo[2.2.1]heptan-2-yl fluoromethyl ketone; 2-Fluoroacetylbicyclo[2.2.1]heptane; 917373-36-5; 2-(Fluoroacetyl)-2-norbornane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.