Description

(2-(2,5-Difluorophenyl)Cyclopropyl)Methanol is a high-purity fluorinated cyclopropane derivative, a critical chiral building block in advanced organic synthesis. This compound matters for its unique structural motif, which combines a strained cyclopropyl ring with a difluorophenyl group, enabling precise modulation of molecular properties in target molecules. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorinated phenyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with tailored electronic and optical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and protein-ligand interactions due to its fluorine labels.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects requiring complex, fluorinated cyclopropane architectures.

Basic Information

Product Name	(2-(2,5-Difluorophenyl)Cyclopropyl)Methanol
CAS No.	917342-18-8
Molecular Formula	C10H10F2O
Molecular Weight	184.18 g/mol
Synonyms	2-(2,5-Difluorophenyl)cyclopropanemethanol; (2-(2,5-Difluorophenyl)cyclopropyl)methanol; 1-(2,5-Difluorophenyl)-2-(hydroxymethyl)cyclopropane; α-(2,5-Difluorophenyl)cyclopropanemethanol; 2,5-Difluoro-α-(hydroxymethyl)benzenepropane; Cyclopropanemethanol, 2-(2,5-difluorophenyl)-; (2-(2,5-Difluorophenyl)cyclopropyl)carbinol
EINECS	Contact for details

Quality Control

Our (2-(2,5-Difluorophenyl)Cyclopropyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.