Description

n-[2-(Bromomethyl)-4-Methoxyphenyl]-2,2,2-Trifluoroacetimidoyl Chloride is a high-value, multi-functional organic intermediate characterized by its reactive bromomethyl and trifluoroacetimidoyl chloride groups. This compound is essential for the efficient synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the introduced fluorinated moiety can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and labeled compounds for proteomics and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	n-[2-(Bromomethyl)-4-Methoxyphenyl]-2,2,2-Trifluoroacetimidoyl Chloride
CAS No.	916974-26-0
Molecular Formula	C10H8BrClF3NO
Molecular Weight	330.53 g/mol
Synonyms	2,2,2-Trifluoro-N-[2-(bromomethyl)-4-methoxyphenyl]ethanimidoyl chloride; 1-[2-(Bromomethyl)-4-methoxyphenyl]-2,2,2-trifluoroethanimidoyl chloride; 2-(Bromomethyl)-4-methoxy-α,α,α-trifluoroacetimidoyl chloride; (2-(Bromomethyl)-4-methoxyphenyl)(trifluoroacetyl)imino chloride; 916974-26-0; Bromomethyl methoxyphenyl trifluoroacetimidoyl chloride
EINECS	Contact for details

Quality Control

Our n-[2-(Bromomethyl)-4-Methoxyphenyl]-2,2,2-Trifluoroacetimidoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.