Description

1-(4-Bromo-3-Fluorophenyl)Propan-1-One is a high-purity fluorinated and brominated aromatic ketone building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers and specialty polymers, including liquid crystals and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-Bromo-3-Fluorophenyl)Propan-1-One
CAS No.	916792-04-6
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	1-(4-Bromo-3-fluorophenyl)-1-propanone; 4'-Bromo-3'-fluoropropiophenone; 3-Fluoro-4-bromopropiophenone; Propiophenone, 4'-bromo-3'-fluoro-; 1-Propanone, 1-(4-bromo-3-fluorophenyl)-; 916792-04-6; 4-Bromo-3-fluoropropiophenone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Bromo-3-Fluorophenyl)Propan-1-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.