Description

3-Methoxy-5-(Trifluoromethyl)Benzoyl Chloride is a high-purity, reactive aromatic acid chloride intermediate. This compound is valued for its trifluoromethyl and methoxy substituents, which impart unique electronic and steric properties critical for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly as a key building block in active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom chemical synthesis services catering to biotechnology and fine chemical sectors.

Basic Information

Product Name	3-Methoxy-5-(Trifluoromethyl)Benzoyl Chloride
CAS No.	916420-92-3
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	3-Methoxy-5-(trifluoromethyl)benzoyl chloride; 5-(Trifluoromethyl)-3-methoxybenzoyl chloride; m-Methoxy-α,α,α-trifluoro-m-toluoyl chloride; 3-Methoxy-α,α,α-trifluoro-m-toluoyl chloride; 3-Methoxy-5-trifluoromethylbenzoyl chloride; 916420-92-3; Benzoyl chloride, 3-methoxy-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Methoxy-5-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.