Description

2-[(tert-Butyl)Amino]Acetyl Chloride Hydrochloride is a high-purity, reactive chemical intermediate used in advanced organic synthesis. This compound is critical for the efficient introduction of the tert-butylaminoacetyl moiety, a valuable functional group in medicinal chemistry. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides requiring specific amine functionalities.
• Peptide Mimetics & Modifications: Facilitates the incorporation of N-tert-butyl glycine analogs into peptide chains to enhance metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis.
• Custom Chemical Synthesis: Employed in contract research and manufacturing (CRO/CMO) for producing bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	2-[(tert-Butyl)Amino]Acetyl Chloride Hydrochloride
CAS No.	915725-52-9
Molecular Formula	C8H17Cl2NO
Molecular Weight	214.13 g/mol
Synonyms	N-(tert-Butyl)chloroacetamide Hydrochloride; 2-Chloro-N-(tert-butyl)acetamide Hydrochloride; (2-Chloro-1-oxoethyl)(tert-butyl)ammonium Chloride; tert-Butylaminoacetyl Chloride Hydrochloride; 2-(tert-Butylamino)acetyl Chloride HCl; Chloroacetic Acid tert-Butylamide Hydrochloride; N-tert-Butylchloroacetamide Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[(tert-Butyl)Amino]Acetyl Chloride Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.