Description

2, 3''-Diamino-2'', 3''-Dideoxyadenosine (3''-Amino-2'', 3''-Dideoxy-2, 6-Diaminopurineriboside) is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. Research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers require this high-purity intermediate for developing next-generation nucleotide-based therapies. Its unique structure, featuring dual amino groups on a dideoxyribose scaffold, allows for precise molecular modifications to enhance drug efficacy and specificity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) for hepatitis, HIV, and other viral diseases.
• Anticancer Agent Development: Serves as a scaffold for creating compounds that interfere with DNA/RNA synthesis in rapidly dividing cells.
• Biochemical Probe Synthesis: Utilized to create labeled or modified nucleotides for studying enzyme mechanisms and cellular processes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Academic & Contract Research: Essential for basic research in biochemistry, molecular biology, and pharmacology at universities and CROs.

Basic Information

Product Name	2, 3''-Diamino-2'', 3''-Dideoxyadenosine (3''-Amino-2'', 3''-Dideoxy-2, 6-Diaminopurineriboside)
CAS No.	915399-37-0
Molecular Formula	C10H14N8O2
Molecular Weight	278.27 g/mol
Synonyms	3'-Amino-2',3'-dideoxy-2,6-diaminopurineriboside; 2,3'-Diamino-2',3'-dideoxyadenosine; 2,6-Diamino-9-(3-amino-2,3-dideoxy-β-D-ribofuranosyl)purine; 9-[(2S,3S)-3-Amino-2,3-dideoxy-β-D-erythro-pentofuranosyl]-2,6-diaminopurine; Dideoxyadenosine diamine derivative; Nucleoside analog intermediate; 2',3'-Dideoxy-2,3'-diaminoadenosine
EINECS	Contact for details

Quality Control

Our 2, 3''-Diamino-2'', 3''-Dideoxyadenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While produced to meet the exacting standards of pharmaceutical R&D, specific grade customization (e.g., USP, EP) is available upon request to align with your project's regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Total area normalization)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.