Description

1-Bromo-1-(4-Chloro-3-(Methylsulfonyl)Phenyl)Propan-2-One is a high-value, multi-functional organic intermediate featuring a unique halogenated aryl ketone structure. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require advanced chemical synthesis, such as pharmaceutical R&D, crop protection, and specialty chemical manufacturing, need this precise intermediate for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its reactive bromine and chlorophenyl groups for potent biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Specialty Chemical Manufacturing: Employed in the production of advanced materials, including liquid crystals and photoactive compounds, due to its specific electronic properties.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Functional Group Transformation: Utilized as a starting material for further chemical modifications, such as reduction to alcohols or conversion to other halogenated derivatives.

Basic Information

Product Name	1-Bromo-1-(4-Chloro-3-(Methylsulfonyl)Phenyl)Propan-2-One
CAS No.	914382-89-1
Molecular Formula	C10H10BrClO3S
Molecular Weight	325.60 g/mol
Synonyms	2-Propanone, 1-bromo-1-[4-chloro-3-(methylsulfonyl)phenyl]-; 1-(4-Chloro-3-methanesulfonylphenyl)-2-bromopropan-1-one; α-Bromo-4'-chloro-3'-(methylsulfonyl)propiophenone; 2-Bromo-1-(4-chloro-3-(methylsulfonyl)phenyl)propan-1-one; Propiophenone, 2-bromo-1-(4-chloro-3-(methylsulfonyl)phenyl)-; 914382-89-1; Bromo Chloro Methylsulfonyl Propiophenone Derivative
EINECS	Contact for details

Quality Control

Our 1-Bromo-1-(4-Chloro-3-(Methylsulfonyl)Phenyl)Propan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material is suitable for demanding applications in GMP-compliant pharmaceutical synthesis and other critical industrial processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.