Description

Fosravuconazole L-Lysine Ethanolate is a high-purity, non-racemic salt form of the potent triazole antifungal agent, fosravuconazole. This specific ethanolate complex is engineered to enhance the stability and handling properties of the active pharmaceutical ingredient, making it a critical intermediate for advanced pharmaceutical manufacturing. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development and production of next-generation systemic antifungal therapies targeting serious fungal infections.

Application

• Pharmaceutical Intermediate: Serves as a key starting material (KSM) or advanced intermediate in the synthesis of finished dosage forms of fosravuconazole.
• Antifungal Drug Development: Used in preclinical and clinical research for developing new antifungal medications, particularly for invasive aspergillosis and candidiasis.
• Reference Standard: Employed as a high-purity chemical reference standard in analytical laboratories for quality control and method validation.
• Formulation Studies: Utilized in pharmaceutical R&D for studying salt forms, stability, and bioavailability in novel drug formulations.
• Process Chemistry: Applied in scaling up and optimizing synthetic routes for the commercial production of antifungal APIs.

Basic Information

Product Name	Fosravuconazole L-Lysine Ethanolate
CAS No.	914361-45-8
Molecular Formula	C23H32F2N8O3 • C6H14N2O2 • C2H6O
Molecular Weight	Contact for details
Synonyms	Fosravuconazole L-Lysine Ethanolate; (2R,3R)-2-(2,4-Difluorophenyl)-3-(5-{4-[4-(2,2,3,3-Tetrafluoropropoxy)phenyl]-1-piperazinyl}-1H-1,2,4-triazol-1-yl)butyl L-Lysinate Ethanolate; Ravuconazole Fosravuconazole L-Lysine Ethanolate; BMS-379224 L-Lysine Ethanolate; E-1224 L-Lysine Ethanolate Salt; Fosravuconazole Lysine Ethanolate; Antifungal Agent E1224 Ethanolate
EINECS	Contact for details

Quality Control

Our Fosravuconazole L-Lysine Ethanolate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.